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532 Treatment of C2C12 myotubes with Metrnl increases glucose uptake through the calcium-dependent p38 MAPK and AMPK2 pathways and regulates the binding of HDAC5 to the GLUT4 promoter in an AMPK2-dependent manner, promoting GLUT4 transcriptional activation

Exosomes are nano-sized vesicles (50150 nm) that are released from cells into the extracellular space (Thery et al., 2002)

Development of hyaluronic acid-based hydrogels for chronic diabetic wound healing: A review

Supplementary file 1 Fig

Crucially, GHK-Cu upregulates the synthesis of healthy, organized collagen, while simultaneously downregulating the synthesis of disorganized, excessive collagen often seen in problematic scars